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Antenatal Hypoxia and Programming of Glucocorticoid Receptor Expression in the Adult Rat Heart
Glucocorticoid receptor (GR) signaling is critical for development and function of the heart. Our previous study demonstrated that gestational hypoxia induced epigenetic repression of the GR gene in the developing heart. The present study aims to determine that the alterations of promoter methylatio...
Autores principales: | Lv, Juanxiu, Ma, Qingyi, Dasgupta, Chiranjib, Xu, Zhice, Zhang, Lubo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454194/ https://www.ncbi.nlm.nih.gov/pubmed/31001129 http://dx.doi.org/10.3389/fphys.2019.00323 |
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