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Neuromuscular dysfunction, independent of gait dysfunction, modulates trabecular bone homeostasis in mice

OBJECTIVES: To clarify the effects of neuromuscular dysfunction on hindlimb loading, muscle atrophy, and bone homeostasis. METHODS: We quantified changes to hindlimb loading, muscle atrophy, and bone morphology following either Botulinum toxin A (BTxA) induced muscle paralysis or peripheral nerve in...

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Detalles Bibliográficos
Autores principales: Bain, Steven D., Huber, Philippe, Ausk, Brandon J., Kwon, Ronald Y., Gardiner, Edith M., Srinivasan, Sundar, Gross, Ted S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Society of Musculoskeletal and Neuronal Interactions 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454260/
https://www.ncbi.nlm.nih.gov/pubmed/30839306