Estradiol matrix patches for pubertal induction: stability of cut pieces at different temperatures

OBJECTIVE: Transdermal estradiol patches are primarily designed for adult women. No low-dose patches are licensed for pubertal induction in hypogonadal girls. Low doses can be achieved by cutting a matrix patch into smaller pieces. However, the manufacturers do not guarantee stability or utility of...

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Detalles Bibliográficos
Autores principales: Ankarberg-Lindgren, Carina, Gawlik, Aneta, Kriström, Berit, Mazzanti, Laura, Ruijgrok, Elisabeth J, Sas, Theo C J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454296/
https://www.ncbi.nlm.nih.gov/pubmed/30851161
http://dx.doi.org/10.1530/EC-19-0025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454296/
https://www.ncbi.nlm.nih.gov/pubmed/30851161
http://dx.doi.org/10.1530/EC-19-0025

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