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Emergency treatment of adrenal crisis with prednisone suppositories: a bioequivalence study in female patients with Addison’s disease

OBJECTIVE: Patients with adrenal insufficiency (AI) need to adapt their glucocorticoid replacement under stressful conditions to prevent adrenal crisis (AC). Prednisone (PN) suppositories are used for emergency treatment. Pharmacokinetics of 100 mg PN suppositories after vaginal or rectal administra...

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Detalles Bibliográficos
Autores principales: Burger-Stritt, Stephanie, Bachmann, Linda, Kurlbaum, Max, Hahner, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454300/
https://www.ncbi.nlm.nih.gov/pubmed/30952111
http://dx.doi.org/10.1530/EC-19-0024