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Effective cancer immunotherapy by natural mouse conventional type-1 dendritic cells bearing dead tumor antigen
BACKGROUND: The manipulation of dendritic cells (DCs) for cancer vaccination has not reached its full potential, despite the revolution in cancer immunotherapy. DCs are fundamental for CD8+ T cell activation, which relies on cross-presentation of exogenous antigen on MHC-I and can be fostered by imm...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454603/ https://www.ncbi.nlm.nih.gov/pubmed/30961656 http://dx.doi.org/10.1186/s40425-019-0565-5 |