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Ranking genomic features using an information-theoretic measure of epigenetic discordance

BACKGROUND: Establishment and maintenance of DNA methylation throughout the genome is an important epigenetic mechanism that regulates gene expression whose disruption has been implicated in human diseases like cancer. It is therefore crucial to know which genes, or other genomic features of interes...

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Detalles Bibliográficos
Autores principales: Jenkinson, Garrett, Abante, Jordi, Koldobskiy, Michael A., Feinberg, Andrew P., Goutsias, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454630/
https://www.ncbi.nlm.nih.gov/pubmed/30961526
http://dx.doi.org/10.1186/s12859-019-2777-6