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Ranking genomic features using an information-theoretic measure of epigenetic discordance
BACKGROUND: Establishment and maintenance of DNA methylation throughout the genome is an important epigenetic mechanism that regulates gene expression whose disruption has been implicated in human diseases like cancer. It is therefore crucial to know which genes, or other genomic features of interes...
Autores principales: | Jenkinson, Garrett, Abante, Jordi, Koldobskiy, Michael A., Feinberg, Andrew P., Goutsias, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454630/ https://www.ncbi.nlm.nih.gov/pubmed/30961526 http://dx.doi.org/10.1186/s12859-019-2777-6 |
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