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Novel lncRNA-IUR suppresses Bcr-Abl-induced tumorigenesis through regulation of STAT5-CD71 pathway

BACKGROUND: Long noncoding RNAs (lncRNAs), defined as the transcripts longer than 200 nt without protein-coding capacity, have been found to be aberrantly expressed in diverse human diseases including cancer. A reciprocal translocation between chromosome 9 and 22 generates the chimeric Bcr-Abl oncog...

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Detalles Bibliográficos
Autores principales: Wang, Xuefei, Yang, Jianling, Guo, Guijie, Feng, Riyue, Chen, Ke, Liao, Yuan, Zhang, Lianfeng, Sun, Liping, Huang, Shile, Chen, Ji-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454664/
https://www.ncbi.nlm.nih.gov/pubmed/30961617
http://dx.doi.org/10.1186/s12943-019-1013-3