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Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study

BACKGROUND: Warfarin is a widely used oral anticoagulant. Determining the correct dose required to maintain the international normalised ratio (INR) within a therapeutic range can be challenging. In a previous trial, we showed that a dosing algorithm incorporating point-of-care genotyping informatio...

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Detalles Bibliográficos
Autores principales: Jorgensen, Andrea L., Prince, Clare, Fitzgerald, Gail, Hanson, Anita, Downing, Jennifer, Reynolds, Julia, Zhang, J. Eunice, Alfirevic, Ana, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454722/
https://www.ncbi.nlm.nih.gov/pubmed/30961588
http://dx.doi.org/10.1186/s12916-019-1308-7