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Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study
BACKGROUND: Warfarin is a widely used oral anticoagulant. Determining the correct dose required to maintain the international normalised ratio (INR) within a therapeutic range can be challenging. In a previous trial, we showed that a dosing algorithm incorporating point-of-care genotyping informatio...
Autores principales: | Jorgensen, Andrea L., Prince, Clare, Fitzgerald, Gail, Hanson, Anita, Downing, Jennifer, Reynolds, Julia, Zhang, J. Eunice, Alfirevic, Ana, Pirmohamed, Munir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454722/ https://www.ncbi.nlm.nih.gov/pubmed/30961588 http://dx.doi.org/10.1186/s12916-019-1308-7 |
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