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Neutrophil CD64 expression levels in IGRA-positive individuals distinguish latent tuberculosis from active disease

BACKGROUND: CD64 (FcγR1) is a high-affinity receptor for monomeric IgG1 and IgG3. Circulating neutrophils express very low amounts of CD64 on their surface. OBJECTIVES: Our primary aim was to investigate the utility of neutrophil CD64 surface expression as a biomarker of active pulmonary tuberculosi...

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Detalles Bibliográficos
Autores principales: Corrêa, Raquel da Silva, Rodrigues, Luciana Silva, Pereira, Leticia Hagge Lima, Nogueira, Otto Castro, Leung, Janaína, Sousa, Marcela da S, Hacker, Mariana de Andrea, de Siqueira, Helio Ribeiro, Capone, Domênico, Alves, Rogério Lopes Rufino, Pessolani, Maria Cristina Vidal, Schmitz, Veronica, Pereira, Geraldo Moura Batista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454854/
https://www.ncbi.nlm.nih.gov/pubmed/30970080
http://dx.doi.org/10.1590/0074-02760180579