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Lysosomal pH Is Regulated in a Sex Dependent Manner in Immune Cells Expressing CXorf21
Background: CXorf21 and SLC15a4 both contain risk alleles for systemic lupus erythematosus (SLE) and Sjögren's syndrome (pSS). The former escapes X inactivation. Our group predicts specific endolysosomal-dependent immune responses are driven by the protein products of these genes, which form a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454867/ https://www.ncbi.nlm.nih.gov/pubmed/31001245 http://dx.doi.org/10.3389/fimmu.2019.00578 |