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Donor Allospecific CD44(high) Central Memory T Cells Have Decreased Ability to Mediate Graft-vs.-Host Disease

Data from both animal models and humans have demonstrated that effector memory T cells (T(EM)) and central memory T cells (T(CM)) from unprimed donors have decreased ability to induce graft-vs-host disease (GVHD). Allospecific T(EM) from primed donors do not mediate GVHD. However, the potential of a...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Mo, Wenjian, Jiang, Jieling, Chao, Nelson J., Chen, Benny J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454869/
https://www.ncbi.nlm.nih.gov/pubmed/31001254
http://dx.doi.org/10.3389/fimmu.2019.00624