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Donor Allospecific CD44(high) Central Memory T Cells Have Decreased Ability to Mediate Graft-vs.-Host Disease
Data from both animal models and humans have demonstrated that effector memory T cells (T(EM)) and central memory T cells (T(CM)) from unprimed donors have decreased ability to induce graft-vs-host disease (GVHD). Allospecific T(EM) from primed donors do not mediate GVHD. However, the potential of a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454869/ https://www.ncbi.nlm.nih.gov/pubmed/31001254 http://dx.doi.org/10.3389/fimmu.2019.00624 |