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The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception

Inhibition of nociceptor activity is important for the prevention of spontaneous pain and hyperalgesia. To identify the critical K(+) channels that regulate nociceptor excitability, we performed a forward genetic screen using a Drosophila larval nociception paradigm. Knockdown of three K(+) channel...

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Detalles Bibliográficos
Autores principales: Walcott, Kia C.E., Mauthner, Stephanie E., Tsubouchi, Asako, Robertson, Jessica, Daniel Tracey, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454897/
https://www.ncbi.nlm.nih.gov/pubmed/30231996
http://dx.doi.org/10.1016/j.celrep.2018.08.070