Cargando…

Housecleaning of pyrimidine nucleotide pool coordinates metabolic adaptation of nongrowing Mycobacterium tuberculosis

The ability of Mycobacterium tuberculosis (Mtb) to adopt a slowly growing or nongrowing state within the host plays a critical role for the bacilli to persist in the face of a prolonged multidrug therapy, establish latency and sustain chronic infection. In our previous study, we revealed that genome...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Kun-Xiong, Wu, Yong-Kai, Tang, Bi-Kui, Zhao, Guo-Ping, Lyu, Liang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455119/
https://www.ncbi.nlm.nih.gov/pubmed/30866758
http://dx.doi.org/10.1080/22221751.2018.1559706