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Housecleaning of pyrimidine nucleotide pool coordinates metabolic adaptation of nongrowing Mycobacterium tuberculosis
The ability of Mycobacterium tuberculosis (Mtb) to adopt a slowly growing or nongrowing state within the host plays a critical role for the bacilli to persist in the face of a prolonged multidrug therapy, establish latency and sustain chronic infection. In our previous study, we revealed that genome...
Autores principales: | Shi, Kun-Xiong, Wu, Yong-Kai, Tang, Bi-Kui, Zhao, Guo-Ping, Lyu, Liang-Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455119/ https://www.ncbi.nlm.nih.gov/pubmed/30866758 http://dx.doi.org/10.1080/22221751.2018.1559706 |
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