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Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein

The Middle-East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus that causes severe and often fatal respiratory disease in humans. Efforts to develop antibody-based therapies have focused on neutralizing antibodies that target the receptor binding domain of the viral spike protein the...

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Detalles Bibliográficos
Autores principales: Widjaja, Ivy, Wang, Chunyan, van Haperen, Rien, Gutiérrez-Álvarez, Javier, van Dieren, Brenda, Okba, Nisreen M.A., Raj, V. Stalin, Li, Wentao, Fernandez-Delgado, Raul, Grosveld, Frank, van Kuppeveld, Frank J. M., Haagmans, Bart L., Enjuanes, Luis, Drabek, Dubravka, Bosch, Berend-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455120/
https://www.ncbi.nlm.nih.gov/pubmed/30938227
http://dx.doi.org/10.1080/22221751.2019.1597644