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Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model

Influenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In addition, serological evidence suggests that humans working with poultry are exposed to these viruses. While H4 viruses...

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Detalles Bibliográficos
Autores principales: Amanat, Fatima, Meade, Philip, Strohmeier, Shirin, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455122/
https://www.ncbi.nlm.nih.gov/pubmed/30866770
http://dx.doi.org/10.1080/22221751.2018.1564369