Immunization with whole cell but not acellular pertussis vaccines primes CD4 T(RM) cells that sustain protective immunity against nasal colonization with Bordetella pertussis

Protective immunity wanes rapidly after immunization of children with acellular pertussis (aP) vaccines and these vaccines do not prevent nasal colonization or transmission of Bordetella pertussis in baboons. In this study, we examined the role of tissue-resident memory T (T(RM)) cells in persistent...

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Detalles Bibliográficos
Autores principales: Wilk, Mieszko M., Borkner, Lisa, Misiak, Alicja, Curham, Lucy, Allen, Aideen C., Mills, Kingston H. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455184/
https://www.ncbi.nlm.nih.gov/pubmed/30866771
http://dx.doi.org/10.1080/22221751.2018.1564630

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455184/
https://www.ncbi.nlm.nih.gov/pubmed/30866771
http://dx.doi.org/10.1080/22221751.2018.1564630

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