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Gene conversion homogenizes the CMT1A paralogous repeats

BACKGROUND: Non-allelic homologous recombination between paralogous repeats is increasingly being recognized as a major mechanism causing both pathogenic microdeletions and duplications, and structural polymorphism in the human genome. It has recently been shown empirically that gene conversion can...

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Detalles Bibliográficos
Autor principal: Hurles, Matthew E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64552/
https://www.ncbi.nlm.nih.gov/pubmed/11801183
http://dx.doi.org/10.1186/1471-2164-2-11