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Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways

INTRODUCTION: Lumbar radicular pain after disk herniation is associated with local release of many inflammatory molecules from nucleus pulposus (NP) cells leaking out of the intervertebral disk. Here, we have used a rat model to investigate the role of epiregulin (EREG), a member of the epidermal gr...

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Detalles Bibliográficos
Autores principales: Kongstorp, Mette, Schjølberg, Tiril, Jacobsen, Daniel Pitz, Haugen, Fred, Gjerstad, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6455685/
https://www.ncbi.nlm.nih.gov/pubmed/31041419
http://dx.doi.org/10.1097/PR9.0000000000000718