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Validation of publicly-available software used in analyzing NGS data for HIV-1 drug resistance mutations and transmission networks in a Washington, DC, Cohort

The DC Cohort is an ongoing longitudinal observational study of persons living with HIV. To better understand HIV-1 drug resistance and potential transmission clusters among these participants, we performed targeted, paired-end next-generation sequencing (NGS) of protease, reverse transcriptase and...

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Detalles Bibliográficos
Autores principales: Jair, Kamwing, McCann, Chase D., Reed, Harrison, Castel, Amanda D., Pérez-Losada, Marcos, Wilbourn, Brittany, Greenberg, Alan E., Jordan, Jeanne A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456221/
https://www.ncbi.nlm.nih.gov/pubmed/30964884
http://dx.doi.org/10.1371/journal.pone.0214820