Cargando…

Mitochondrial function remains impaired in the hypertrophied right ventricle of pulmonary hypertensive rats following short duration metoprolol treatment

Pulmonary hypertension (PH) increases the work of the right ventricle (RV) and causes right-sided heart failure. This study examined RV mitochondrial function and ADP transfer in PH animals advancing to right heart failure, and investigated a potential therapy with the specific β(1)-adrenergic-block...

Descripción completa

Detalles Bibliográficos
Autores principales: Power, Amelia S., Norman, Ruth, Jones, Timothy L. M., Hickey, Anthony J., Ward, Marie-Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456253/
https://www.ncbi.nlm.nih.gov/pubmed/30964911
http://dx.doi.org/10.1371/journal.pone.0214740