Structure and mechanism of a Hypr GGDEF enzyme that activates cGAMP signaling to control extracellular metal respiration

A newfound signaling pathway employs a GGDEF enzyme with unique activity compared to the majority of homologs associated with bacterial cyclic di-GMP signaling. This system provides a rare opportunity to study how signaling proteins natively gain distinct function. Using genetic knockouts, riboswitc...

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Detalles Bibliográficos
Autores principales: Hallberg, Zachary F, Chan, Chi Ho, Wright, Todd A, Kranzusch, Philip J, Doxzen, Kevin W, Park, James J, Bond, Daniel R, Hammond, Ming C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456294/
https://www.ncbi.nlm.nih.gov/pubmed/30964001
http://dx.doi.org/10.7554/eLife.43959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456294/
https://www.ncbi.nlm.nih.gov/pubmed/30964001
http://dx.doi.org/10.7554/eLife.43959

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