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Structure and mechanism of a Hypr GGDEF enzyme that activates cGAMP signaling to control extracellular metal respiration

A newfound signaling pathway employs a GGDEF enzyme with unique activity compared to the majority of homologs associated with bacterial cyclic di-GMP signaling. This system provides a rare opportunity to study how signaling proteins natively gain distinct function. Using genetic knockouts, riboswitc...

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Detalles Bibliográficos
Autores principales:	Hallberg, Zachary F, Chan, Chi Ho, Wright, Todd A, Kranzusch, Philip J, Doxzen, Kevin W, Park, James J, Bond, Daniel R, Hammond, Ming C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456294/ https://www.ncbi.nlm.nih.gov/pubmed/30964001 http://dx.doi.org/10.7554/eLife.43959

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