Transcriptional down-regulation of ccr5 in a subset of HIV+ controllers and their family members

HIV +Elite and Viremic controllers (EC/VCs) are able to control virus infection, perhaps because of host genetic determinants. We identified 16% (21 of 131) EC/VCs with CD4 +T cells with resistance specific to R5-tropic HIV, reversed after introduction of ccr5. R5 resistance was not observed in macr...

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Detalles Bibliográficos
Autores principales: Gonzalo-Gil, Elena, Rapuano, Patrick B, Ikediobi, Uchenna, Leibowitz, Rebecca, Mehta, Sameet, Coskun, Ayse K, Porterfield, J Zachary, Lampkin, Teagan D, Marconi, Vincent C, Rimland, David, Walker, Bruce D, Deeks, Steven, Sutton, Richard E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456299/
https://www.ncbi.nlm.nih.gov/pubmed/30964004
http://dx.doi.org/10.7554/eLife.44360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456299/
https://www.ncbi.nlm.nih.gov/pubmed/30964004
http://dx.doi.org/10.7554/eLife.44360

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