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Acetylcholinesterase assay for cerebrospinal fluid using bupivacaine to inhibit butyrylcholinesterase

BACKGROUND: Most test systems for acetylcholinesterase activity (E.C.3.1.1.7.) are using toxic inhibitors (BW284c51 and iso-OMPA) to distinguish the enzyme from butyrylcholinesterase (E.C.3.1.1.8.) which occurs simultaneously in the cerebrospinal fluid. Applying Ellman's colorimetric method, we...

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Detalles Bibliográficos
Autores principales: Kluge, Wolfram H, Kluge, Harald H, Bauer, Heike I, Pietsch, Stefan, Anders, Jens, Venbrocks, Rudolf A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC64563/
https://www.ncbi.nlm.nih.gov/pubmed/11801199
http://dx.doi.org/10.1186/1471-2091-2-17