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Modeling Heterogeneity in the Genetic Architecture of Ethnically Diverse Groups Using Random Effect Interaction Models

In humans, most genome-wide association studies have been conducted using data from Caucasians and many of the reported findings have not replicated in other populations. This lack of replication may be due to statistical issues (small sample sizes or confounding) or perhaps more fundamentally to di...

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Detalles Bibliográficos
Autores principales: Veturi, Yogasudha, de los Campos, Gustavo, Yi, Nengjun, Huang, Wen, Vazquez, Ana I., Kühnel, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456318/
https://www.ncbi.nlm.nih.gov/pubmed/30796011
http://dx.doi.org/10.1534/genetics.119.301909