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Deletion of Dtnbp1 in mice impairs threat memory consolidation and is associated with enhanced inhibitory drive in the amygdala
Schizophrenia is a severe and highly heritable disorder. Dystrobrevin-binding protein 1 (DTNBP1), also known as dysbindin-1, has been implicated in the pathophysiology of schizophrenia. Specifically, dysbindin-1 mRNA and protein expression are decreased in the brains of subjects with this disorder....
Autores principales: | Huang, Cathy C. Y., Muszynski, Kevin J., Bolshakov, Vadim Y., Balu, Darrick T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456574/ https://www.ncbi.nlm.nih.gov/pubmed/30967545 http://dx.doi.org/10.1038/s41398-019-0465-y |
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