p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance

Immunoregulatory protein B7-H3 is involved in the oncogenic and metastatic potential of cancer cells, as well as in drug resistance. Resistance to conventional chemotherapy is an important aspect of melanoma treatment, and a better understanding of how B7-H3 enhances drug resistance may lead to the...

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Detalles Bibliográficos
Autores principales: Flem-Karlsen, Karine, Tekle, Christina, Øyjord, Tove, Flørenes, Vivi A., Mælandsmo, Gunhild M., Fodstad, Øystein, Nunes-Xavier, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456585/
https://www.ncbi.nlm.nih.gov/pubmed/30967582
http://dx.doi.org/10.1038/s41598-019-42303-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456585/
https://www.ncbi.nlm.nih.gov/pubmed/30967582
http://dx.doi.org/10.1038/s41598-019-42303-w

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