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p38 MAPK activation through B7-H3-mediated DUSP10 repression promotes chemoresistance
Immunoregulatory protein B7-H3 is involved in the oncogenic and metastatic potential of cancer cells, as well as in drug resistance. Resistance to conventional chemotherapy is an important aspect of melanoma treatment, and a better understanding of how B7-H3 enhances drug resistance may lead to the...
Autores principales: | Flem-Karlsen, Karine, Tekle, Christina, Øyjord, Tove, Flørenes, Vivi A., Mælandsmo, Gunhild M., Fodstad, Øystein, Nunes-Xavier, Caroline E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456585/ https://www.ncbi.nlm.nih.gov/pubmed/30967582 http://dx.doi.org/10.1038/s41598-019-42303-w |
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