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LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly regulate neutrophil extravasation through hotspots I and II

Precise spatiotemporal regulation of leukocyte extravasation is key for generating an efficient immune response to injury or infection. The integrins LFA-1(CD11a/CD18) and Mac-1(CD11b/CD18) play overlapping roles in neutrophil migration because they bind the same as well as different ligands in resp...

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Detalles Bibliográficos
Autores principales: Hyun, Young-Min, Choe, Young Ho, Park, Sang A., Kim, Minsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456621/
https://www.ncbi.nlm.nih.gov/pubmed/30967528
http://dx.doi.org/10.1038/s12276-019-0227-1