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Application of a Dual Internally Quenched Fluorogenic Substrate in Screening for D-Arginine Specific Proteases

The application of D-stereospecific proteases (DSPs) in resolution of racemic amino acids and in the semisynthesis of proteins has been a successful strategy. The main limitation for a broader application is, however, the accessibility of suitable DSPs covering multiple substrate specificities. To i...

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Detalles Bibliográficos
Autores principales: Simon, Andreas H., Liebscher, Sandra, Aumüller, Tobias H., Treblow, Dennis, Bordusa, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456654/
https://www.ncbi.nlm.nih.gov/pubmed/31001242
http://dx.doi.org/10.3389/fmicb.2019.00711