Protein Misfolding and ER Stress in Huntington's Disease

Increasing evidence in recent years indicates that protein misfolding and aggregation, leading to ER stress, are central factors of pathogenicity in neurodegenerative diseases. This is particularly true in Huntington's disease (HD), where in contrast with other disorders, the cause is monogenic...

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Detalles Bibliográficos
Autores principales: Shacham, Talya, Sharma, Neeraj, Lederkremer, Gerardo Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456712/
https://www.ncbi.nlm.nih.gov/pubmed/31001537
http://dx.doi.org/10.3389/fmolb.2019.00020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456712/
https://www.ncbi.nlm.nih.gov/pubmed/31001537
http://dx.doi.org/10.3389/fmolb.2019.00020

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