Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics

Brown and beige adipocytes are enriched in mitochondria with uncoupling protein-1 (UCP1) to generate heat instead of ATP contributing to healthy energy balance. There are few human cellular models to reveal regulatory networks in adipocyte browning and key targets for enhancing thermogenesis in obes...

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Detalles Bibliográficos
Autores principales: Klusóczki, Ágnes, Veréb, Zoltán, Vámos, Attila, Fischer-Posovszky, Pamela, Wabitsch, Martin, Bacso, Zsolt, Fésüs, László, Kristóf, Endre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456729/
https://www.ncbi.nlm.nih.gov/pubmed/30967578
http://dx.doi.org/10.1038/s41598-019-42256-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456729/
https://www.ncbi.nlm.nih.gov/pubmed/30967578
http://dx.doi.org/10.1038/s41598-019-42256-0

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