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Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics
Brown and beige adipocytes are enriched in mitochondria with uncoupling protein-1 (UCP1) to generate heat instead of ATP contributing to healthy energy balance. There are few human cellular models to reveal regulatory networks in adipocyte browning and key targets for enhancing thermogenesis in obes...
Autores principales: | Klusóczki, Ágnes, Veréb, Zoltán, Vámos, Attila, Fischer-Posovszky, Pamela, Wabitsch, Martin, Bacso, Zsolt, Fésüs, László, Kristóf, Endre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456729/ https://www.ncbi.nlm.nih.gov/pubmed/30967578 http://dx.doi.org/10.1038/s41598-019-42256-0 |
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