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JC Polyomavirus Uses Extracellular Vesicles To Infect Target Cells

The endemic human JC polyomavirus (JCPyV) causes progressive multifocal leukoencephalopathy in immune-suppressed patients. The mechanisms of virus infection in vivo are not understood because the major target cells for virus in the brain do not express virus receptors and do not bind virus. We found...

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Detalles Bibliográficos
Autores principales: Morris-Love, Jenna, Gee, Gretchen V., O’Hara, Bethany A., Assetta, Benedetta, Atkinson, Abigail L., Dugan, Aisling S., Haley, Sheila A., Atwood, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456752/
https://www.ncbi.nlm.nih.gov/pubmed/30967463
http://dx.doi.org/10.1128/mBio.00379-19