Glibenclamide ameliorates the disrupted blood–brain barrier in experimental intracerebral hemorrhage by inhibiting the activation of NLRP3 inflammasome

BACKGROUND: Glibenclamide is a widely used sulfonylurea drug prescribed to treat type II diabetes mellitus. Previous studies have demonstrated that glibenclamide has neuroprotective effects in central nervous system injury. However, the exact mechanism by which glibenclamide acts on the blood–brain...

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Detalles Bibliográficos
Autores principales: Xu, Fulin, Shen, Gang, Su, Zuopeng, He, Zijian, Yuan, Lutao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456786/
https://www.ncbi.nlm.nih.gov/pubmed/30859754
http://dx.doi.org/10.1002/brb3.1254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456786/
https://www.ncbi.nlm.nih.gov/pubmed/30859754
http://dx.doi.org/10.1002/brb3.1254

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