Cargando…

Glibenclamide ameliorates the disrupted blood–brain barrier in experimental intracerebral hemorrhage by inhibiting the activation of NLRP3 inflammasome

BACKGROUND: Glibenclamide is a widely used sulfonylurea drug prescribed to treat type II diabetes mellitus. Previous studies have demonstrated that glibenclamide has neuroprotective effects in central nervous system injury. However, the exact mechanism by which glibenclamide acts on the blood–brain...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Fulin, Shen, Gang, Su, Zuopeng, He, Zijian, Yuan, Lutao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456786/ https://www.ncbi.nlm.nih.gov/pubmed/30859754 http://dx.doi.org/10.1002/brb3.1254

Ejemplares similares

NLRP6 Inflammasome Ameliorates Brain Injury after Intracerebral Hemorrhage
por: Wang, Peng-Fei, et al.
Publicado: (2017)

Interplay between Gut Microbiota and NLRP3 Inflammasome in Intracerebral Hemorrhage
por: Zhang, Yuan, et al.
Publicado: (2022)

Glibenclamide Attenuates Neuroinflammation and Promotes Neurological Recovery After Intracerebral Hemorrhage in Aged Rats
por: Jiang, Bing, et al.
Publicado: (2021)

Vascular disruption and blood–brain barrier dysfunction in intracerebral hemorrhage
por: Keep, Richard F, et al.
Publicado: (2014)

Glibenclamide does not improve outcome following severe collagenase-induced intracerebral hemorrhage in rats
por: Kung, Tiffany F. C., et al.
Publicado: (2021)

A systematic review and meta-analysis on the efficacy of glibenclamide in animal models of intracerebral hemorrhage
por: Kung, Tiffany F. C., et al.
Publicado: (2023)

Resolvin D1 ameliorates Inflammation-Mediated Blood-Brain Barrier Disruption After Subarachnoid Hemorrhage in rats by Modulating A20 and NLRP3 Inflammasome
por: Wei, Chengcong, et al.
Publicado: (2021)

Glibenclamide Alleviates LPS-Induced Acute Lung Injury through NLRP3 Inflammasome Signaling Pathway
por: Yang, Jie, et al.
Publicado: (2022)

Glibenclamide alleviates inflammation in oleic acid model of acute lung injury through NLRP3 inflammasome signaling pathway
por: Chen, Hong, et al.
Publicado: (2019)

Glibenclamide for the Treatment of Ischemic and Hemorrhagic Stroke
por: Caffes, Nicholas, et al.
Publicado: (2015)

Neuroprotection of Botch in experimental intracerebral hemorrhage in rats
por: Mei, Binbin, et al.
Publicado: (2017)

Glibenclamide, a Sur1-Trpm4 antagonist, does not improve outcome after collagenase-induced intracerebral hemorrhage
por: Wilkinson, Cassandra M., et al.
Publicado: (2019)

EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption
por: Pinilla, Miriam, et al.
Publicado: (2023)

Inhibition of the NLRP3 Inflammasome Activation by Manoalide Ameliorates Experimental Autoimmune Encephalomyelitis Pathogenesis
por: Li, Cong, et al.
Publicado: (2022)

Genetic deletion or pharmacologic inhibition of the Nlrp3 inflammasome did not ameliorate experimental NASH
por: Ioannou, George N., et al.
Publicado: (2023)

Selective NLRP3 (Pyrin Domain–Containing Protein 3) Inflammasome Inhibitor Reduces Brain Injury After Intracerebral Hemorrhage
por: Ren, Honglei, et al.
Publicado: (2018)

Atorvastatin suppresses NLRP3 inflammasome activation in intracerebral hemorrhage via TLR4- and MyD88-dependent pathways
por: Chen, Duo, et al.
Publicado: (2022)

Secondary White Matter Injury Mediated by Neuroinflammation after Intracerebral Hemorrhage and Promising Therapeutic Strategies of Targeting the NLRP3 Inflammasome
por: Xiao, Linglong, et al.
Publicado: (2023)

Perihematomal glutamate level is associated with the blood–brain barrier disruption in a rabbit model of intracerebral hemorrhage
por: Wu, Guofeng, et al.
Publicado: (2013)

Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid hemorrhage
por: Xia, Dayong, et al.
Publicado: (2023)

Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases
por: Xu, Congfei, et al.
Publicado: (2018)

Rhubarb attenuates blood-brain barrier disruption via increased zonula occludens-1 expression in a rat model of intracerebral hemorrhage
por: WANG, YANG, et al.
Publicado: (2016)

NLRP3 Inflammasome in the Pathophysiology of Hemorrhagic Stroke: A Review
por: Luo, Yujie, et al.
Publicado: (2019)

NLRP3 Inflammasome Overactivation in Patients with Aneurysmal Subarachnoid Hemorrhage
por: Díaz-García, Elena, et al.
Publicado: (2022)

The Protective Effect of Glibenclamide in a Model of Hemorrhagic Encephalopathy of Prematurity
por: Tosun, Cigdem, et al.
Publicado: (2013)

Glibenclamide Advantage in Treating Edema After Intracerebral Hemorrhage (GATE-ICH): Study Protocol for a Multicenter Randomized, Controlled, Assessor-Blinded Trial
por: Zhao, Jingjing, et al.
Publicado: (2021)

Local Experimental Intracerebral Hemorrhage in Rats
por: Vasilevskaya, Ekaterina, et al.
Publicado: (2021)

PHLDA1 modulates microglial response and NLRP3 inflammasome signaling following experimental subarachnoid hemorrhage
por: Lai, Jinqing, et al.
Publicado: (2023)

Low-intensity pulsed ultrasound ameliorates glia-mediated inflammation and neuronal damage in experimental intracerebral hemorrhage conditions
por: Su, Wei-Shen, et al.
Publicado: (2023)

iTRAQ-Based Quantitative Proteomics Indicated Nrf2/OPTN-Mediated Mitophagy Inhibits NLRP3 Inflammasome Activation after Intracerebral Hemorrhage
por: Cheng, Yijun, et al.
Publicado: (2021)

Inhibition of Dectin-1 Alleviates Neuroinflammatory Injury by Attenuating NLRP3 Inflammasome-Mediated Pyroptosis After Intracerebral Hemorrhage in Mice: Preliminary Study Results
por: Ding, Zhiquan, et al.
Publicado: (2022)

Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling
por: Lu, Miaomiao, et al.
Publicado: (2017)

Celastrol ameliorates inflammation through inhibition of NLRP3 inflammasome activation
por: Yu, Xianjun, et al.
Publicado: (2017)

Ketogenic diet ameliorates inflammation by inhibiting the NLRP3 inflammasome in osteoarthritis
por: Kong, Ganggang, et al.
Publicado: (2022)

Ruscogenin Ameliorated Sjögren's Syndrome by Inhibiting NLRP3 Inflammasome Activation
por: He, Jing, et al.
Publicado: (2022)

Berberine ameliorates depression-like behaviors in mice via inhibiting NLRP3 inflammasome-mediated neuroinflammation and preventing neuroplasticity disruption
por: Qin, Zongshi, et al.
Publicado: (2023)

Reversal of experimentally induced seizure activity in mice by glibenclamide
por: Pithadia, Anand B., et al.
Publicado: (2013)

Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC
por: Zhao, Jia, et al.
Publicado: (2023)

The pivotal role of the NLRC4 inflammasome in neuroinflammation after intracerebral hemorrhage in rats
por: Gan, Hui, et al.
Publicado: (2021)

Ghrelin Attenuates Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis Involving NLRP3 Inflammasome Signaling Pathway and Pyroptosis
por: Liu, Fei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ki8lqr6tpfdlrctchss6o8h6k5