Cardioprotective Effect of the Mitochondrial Unfolded Protein Response During Chronic Pressure Overload

BACKGROUND: The mitochondrial unfolded protein response (UPR(mt)) is activated when misfolded proteins accumulate within mitochondria and leads to increased expression of mitochondrial chaperones and proteases to maintain protein quality and mitochondrial function. Cardiac mitochondria are essential...

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Detalles Bibliográficos
Autores principales: Smyrnias, Ioannis, Gray, Stephen P., Okonko, Darlington O., Sawyer, Greta, Zoccarato, Anna, Catibog, Norman, López, Begoña, González, Arantxa, Ravassa, Susana, Díez, Javier, Shah, Ajay M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Biomedical 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456800/
https://www.ncbi.nlm.nih.gov/pubmed/30975297
http://dx.doi.org/10.1016/j.jacc.2018.12.087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456800/
https://www.ncbi.nlm.nih.gov/pubmed/30975297
http://dx.doi.org/10.1016/j.jacc.2018.12.087

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