Age, but Not Amyloidosis, Induced Changes in Global Levels of Histone Modifications in Susceptible and Disease-Resistant Neurons in Alzheimer’s Disease Model Mice

There is increasing interest in the role of epigenetic alterations in Alzheimer’s disease (AD). The epigenome of every cell type is distinct, yet data regarding epigenetic change in specific cell types in aging and AD is limited. We investigated histone tail modifications in neuronal subtypes in wil...

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Detalles Bibliográficos
Autores principales: Dyer, Marcus, Phipps, Andrew J., Mitew, Stanislaw, Taberlay, Phillippa C., Woodhouse, Adele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456813/
https://www.ncbi.nlm.nih.gov/pubmed/31001106
http://dx.doi.org/10.3389/fnagi.2019.00068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456813/
https://www.ncbi.nlm.nih.gov/pubmed/31001106
http://dx.doi.org/10.3389/fnagi.2019.00068

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