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Development of a Sensitive, Scalable Method for Spatial, Cell-Type-Resolved Proteomics of the Human Brain

[Image: see text] While nearly comprehensive proteome coverage can be achieved from bulk tissue or cultured cells, the data usually lacks spatial resolution. As a result, tissue based proteomics averages protein abundance across multiple cell types and/or localizations. With proteomics platforms lac...

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Detalles Bibliográficos
Autores principales: Davis, Simon, Scott, Connor, Ansorge, Olaf, Fischer, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456870/
https://www.ncbi.nlm.nih.gov/pubmed/30768908
http://dx.doi.org/10.1021/acs.jproteome.8b00981