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Pre-fractionation Extends but also Creates a Bias in the Detectable HLA Class Ι Ligandome
[Image: see text] HLA class Ι molecules can communicate a range of cellular alterations (mutations, changes in protein copy number, aberrant post-translational modifications, or pathogen proteins) to CD8+ T lymphocytes in the form of HLA peptide ligands. At any given moment, tens of thousands of dif...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456874/ https://www.ncbi.nlm.nih.gov/pubmed/30784271 http://dx.doi.org/10.1021/acs.jproteome.8b00821 |