CDK7 is a component of the integrated stress response regulating SNAT2 (SLC38A2)/System A adaptation in response to cellular amino acid deprivation

Extracellular amino acid (AA) withdrawal/restriction invokes an integrated stress response (ISR) that induces global suppression of protein synthesis whilst allowing transcription and translation of a select group of genes, whose protein products facilitate cellular adaptation to AA insufficiency. T...

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Detalles Bibliográficos
Autores principales: Stretton, Clare, Lipina, Christopher, Hyde, Russell, Cwiklinski, Emma, Hoffmann, Thorsten M., Taylor, Peter M., Hundal, Harinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456927/
https://www.ncbi.nlm.nih.gov/pubmed/30857869
http://dx.doi.org/10.1016/j.bbamcr.2019.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456927/
https://www.ncbi.nlm.nih.gov/pubmed/30857869
http://dx.doi.org/10.1016/j.bbamcr.2019.03.002

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