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GPU accelerated sequence alignment with traceback for GATK HaplotypeCaller

BACKGROUND: Pairwise sequence alignment is widely used in many biological tools and applications. Existing GPU accelerated implementations mainly focus on calculating optimal alignment score and omit identifying the optimal alignment itself. In GATK HaplotypeCaller (HC), the semi-global pairwise seq...

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Detalles Bibliográficos
Autores principales: Ren, Shanshan, Ahmed, Nauman, Bertels, Koen, Al-Ars, Zaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456962/
https://www.ncbi.nlm.nih.gov/pubmed/30967111
http://dx.doi.org/10.1186/s12864-019-5468-9