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Enhanced production of antifungal lipopeptide iturin A by Bacillus amyloliquefaciens LL3 through metabolic engineering and culture conditions optimization

BACKGROUND: Iturins, which belong to antibiotic cyclic lipopeptides mainly produced by Bacillus sp., have the potential for application in biomedicine and biocontrol because of their hemolytic and antifungal properties. Bacillus amyloliquefaciens LL3, isolated previously by our lab, possesses a comp...

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Detalles Bibliográficos
Autores principales: Dang, Yulei, Zhao, Fengjie, Liu, Xiangsheng, Fan, Xu, Huang, Rui, Gao, Weixia, Wang, Shufang, Yang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457013/
https://www.ncbi.nlm.nih.gov/pubmed/30971238
http://dx.doi.org/10.1186/s12934-019-1121-1