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Altered Tryptophan Catabolism in Placentas From Women With Pre-eclampsia

BACKGROUND: The kynurenine pathway enzymes, breaking down tryptophan, are abundant in placental tissue. These metabolites are involved in immunoregulatory mechanisms, although the role of this pathway in pre-eclampsia (PE) has only begun to be characterized. Here, we determined tryptophan and metabo...

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Detalles Bibliográficos
Autores principales: Keaton, Sarah A, Heilman, Patrick, Bryleva, Elena Y, Madaj, Zachary, Krzyzanowski, Stanislaw, Grit, Jamie, Miller, Emily S, Jälmby, Maya, Kalapotharakos, Grigoros, Racicot, Karen, Fazleabas, Asgerally, Hansson, Stefan R, Brundin, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457019/
https://www.ncbi.nlm.nih.gov/pubmed/31007529
http://dx.doi.org/10.1177/1178646919840321