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MRCNN: a deep learning model for regression of genome-wide DNA methylation

BACKGROUND: Determination of genome-wide DNA methylation is significant for both basic research and drug development. As a key epigenetic modification, this biochemical process can modulate gene expression to influence the cell differentiation which can possibly lead to cancer. Due to the involuted...

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Detalles Bibliográficos
Autores principales: Tian, Qi, Zou, Jianxiao, Tang, Jianxiong, Fang, Yuan, Yu, Zhongli, Fan, Shicai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457069/
https://www.ncbi.nlm.nih.gov/pubmed/30967120
http://dx.doi.org/10.1186/s12864-019-5488-5