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Qualitative and Quantitative Analysis of IDH1 Mutation in Progressive Gliomas by Allele-Specific qPCR and Western Blot Analysis

To date, diagnosis of IDH1 mutation is based on DNA sequencing and immunohistochemistry, methods limited in terms of sensitivity and ease of use. Recently, the diagnosis of IDH1 mutation by real-time polymerase chain reaction was introduced as an alternative method. In this study, real-time polymera...

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Detalles Bibliográficos
Autores principales: Perrech, Moritz, Dreher, Lena, Röhn, Gabriele, Stavrinou, Pantelis, Krischek, Boris, Toliat, Mohammad, Goldbrunner, Roland, Timmer, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457076/
https://www.ncbi.nlm.nih.gov/pubmed/30943868
http://dx.doi.org/10.1177/1533033819828396