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Evaluation of HOCl-generating anticancer agents by an ultrasensitive dual-mode fluorescent probe

Hypochlorous acid (HOCl), a reactive oxygen species (ROS), plays a crucial role in the process of pathogenic oxidative stress. Some powerful anticancer agents, such as elesclomol, specifically induce cancer cell apoptosis by increasing HOCl levels. However, sensitive tools to monitor subtle changes...

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Detalles Bibliográficos
Autores principales: Shi, Donglei, Chen, Shuqiang, Dong, Biao, Zhang, Yanhui, Sheng, Chunquan, James, Tony D., Guo, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457194/
https://www.ncbi.nlm.nih.gov/pubmed/31015915
http://dx.doi.org/10.1039/c9sc00180h